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Article

What do we learn from a few familial Alzheimer's disease cases?

Journal of neural transmission. Supplementum - 1 Jan 1998

Haass C, Baumeister R

Abstract excerpt

Alzheimer's disease is the most common form of dementia. About 90% of the cases occur sporadically whereas in 10% of the cases mutations were found within three different genes. Mutations in the gene encoding the beta-Amyloid precursor protein (beta APP) are located in the ultimate neighborhood of the three proteases (secretases) involved in proteolytic processing of beta APP. These mutations cause an increased...

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Source

Identifiers

PMID: 9850922
DOI: 10.1007/978-3-7091-7508-8_13

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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