What the study of persons at risk for familial Alzheimer's disease can tell us about the earliest stages of the disorder: a review.

Abstract excerpt

As the proportion of elderly persons continues to expand, understanding the pathobiology of Alzheimer's disease and being able to diagnose it at an early stage become more critical. A minority of Alzheimer's disease cases are inherited as a fully-penetrant, autosomal dominant trait with a young age of onset. The molecular study of the pathogenic mutations has led to insights regarding the etiology of sporadic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Age of Onset
• Share to Alzheimer Disease
• Share to Biomarkers