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Article

Association between lung cancer and microsomal epoxide hydrolase genotypes.

Cancer research - 1 Dec 1998

Benhamou S, Reinikainen M, Bouchardy C, Dayer P, Hirvonen A

Abstract excerpt

Microsomal epoxide hydrolase (mEH) is involved in the metabolism of tobacco-derived carcinogens. Polymorphisms in exons 3 and 4 of the EPHX gene have been reported to be associated with variations in mEH activity. We examined whether the predicted mEH activity modified the lung cancer risk among...

Topics

Adult
Aged
Carcinoma, Small Cell
Carcinoma, Squamous Cell
Case-Control Studies
Cytochrome P-450 CYP1A1
Epoxide Hydrolases
Exons
Female
Genotype
Glutathione Transferase
Humans
Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Microsomes

Middle Aged

Polymorphism, Genetic

Risk Factors

Source

Identifiers

PMID: 9850050

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9850050-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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