Article
Association between lung cancer and microsomal epoxide hydrolase genotypes.
Cancer research - 1 Dec 1998
Benhamou S, Reinikainen M, Bouchardy C, Dayer P, Hirvonen A
Abstract excerpt
Microsomal epoxide hydrolase (mEH) is involved in the metabolism of tobacco-derived carcinogens. Polymorphisms in exons 3 and 4 of the EPHX gene have been reported to be associated with variations in mEH activity. We examined whether the predicted mEH activity modified the lung cancer risk among 150 cases and 172 controls, all French Caucasian smokers. A significant association was found between predicted mEH...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
