Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of epoxide hydrolase polymorphisms on chromosome aberrations and risk for lung cancer.

Cancer genetics and cytogenetics - 1 Sept 2003

Cajas-Salazar Nohelia, Au William W, Zwischenberger Joseph B, Sierra-Torres Carlos H, Salama Salama A, Alpard Scott K, Tyring Stephen K

Abstract excerpt

Microsomal epoxide hydrolase (mEH) gene is polymorphic and its enzyme is involved in the activation and subsequent detoxification of several tobacco carcinogens, for example polycyclic aromatic hydrocarbons. Therefore, we have investigated the association of two polymorphisms at exons 3 and 4 of the mEH gene with the development of lung cancer in 110 patients and 119 matched controls. In addition, we have...

Topics

Case-Control Studies
Chromosome Aberrations
Epoxide Hydrolases
Female
Genetic Predisposition to Disease
Genotype
Humans
Lung Neoplasms
Male
Middle Aged
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Smoking

Source

Identifiers

PMID: 12935919
DOI: 10.1016/s0165-4608(03)00058-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of epoxide hydrolase polymorphisms on chromosome aberrations and risk for lung cancer.PMID 12935919Read ↗

Microsomal epoxide hydrolase polymorphisms and lung cancer risk: a quantitative reviewSemantic proximity Read ↗

Association between lung cancer and microsomal epoxide hydrolase genotypes.Semantic proximity Read ↗

Genetic analysis of microsomal epoxide hydrolase gene and its association with lung cancer risk.Semantic proximity Read ↗

Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer.Semantic proximity Read ↗

Polymorphisms in the microsomal epoxide hydrolase gene: role in lung cancer susceptibility and prognosis.Semantic proximity Read ↗

Association between environmental tobacco smoke exposure and lung cancer susceptibility: modification by antioxidant enzyme genetic polymorphisms.Semantic proximity Read ↗

Lung cancer susceptibility in relation to combined polymorphisms of microsomal epoxide hydrolase and glutathione S-transferase P1.Semantic proximity Read ↗

High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers.Semantic proximity Read ↗

Genetic polymorphisms in the mEH gene in relation to tobacco smoking: role in lung cancer susceptibility and survival in north Indian patients with lung cancer undergoing platinum-based chemotherapy.Semantic proximity Read ↗

Combined analysis of polymorphisms in glutathione S-transferase M1 and microsomal epoxide hydrolase in lung cancer patients.Semantic proximity Read ↗

Functional polymorphisms of the microsomal epoxide hydrolase gene: a reappraisal on a early-onset lung cancer patients series.Semantic proximity Read ↗

Impact of epoxide hydrolase 1 polymorphisms on lung cancer susceptibility in Asian populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.