Quantitative analysis of yeast gene function using competition experiments in continuous culture.

doi:10.1002/(SICI)1097-0061(199811)14:15<1417::AID-YEA334>3.0.CO;2-N

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Article

Quantitative analysis of yeast gene function using competition experiments in continuous culture.

Yeast (Chichester, England) - 1 Nov 1998

Baganz F, Hayes A, Farquhar R, Butler P R, Gardner D C, Oliver S G

Abstract excerpt

One possible route to the evaluation of gene function is a quantitative approach based on the concepts of metabolic control analysis (MCA). An important first step in such an analysis is to determine the effect of deleting individual genes on the growth rate (or fitness) of S. cerevisiae. Since t...

Topics

Culture Media
DNA, Fungal
Densitometry
Gene Deletion
Genes, Fungal
Mutation
Phenotype
Polymerase Chain Reaction
Reproducibility of Results
Saccharomyces cerevisiae
Sequence Analysis, DNA
Software

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