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Article

The Na+ and K+ transport deficiency of an E. coli mutant lacking the NhaA and NhaB proteins is apparent and caused by impaired osmoregulation.

FEBS letters - 20 Nov 1998

Verkhovskaya M L, Barquera B, Verkhovsky M I, Wikström M

Abstract excerpt

Cells of the E. coli mutant EP432, which lacks the two Na+/H+ antiporters, NhaA and NhaB, have been reported to have an impaired sodium transport activity (Harel-Bronstein et al. (1995) J. Biol. Chem. 270, 3816-3822). Here we report that active transport of Na+ in EP432 cells can be restored to wild-type levels, either by a high K+ concentration or by an increase in the medium osmolarity. We suggest that this...

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PMID: 9845336
DOI: 10.1016/s0014-5793(98)01380-5

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