Article
Leptin attenuates respiratory complications associated with the obese phenotype.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Dec 1998
Tankersley C G, O'Donnell C, Daood M J, Watchko J F, Mitzner W, Schwartz A, Smith P
Abstract excerpt
A profile of respiratory complications has been associated with the onset and development of obesity in humans. Similar phenotypes have been routinely demonstrated in genetic animal models of obesity such as the ob mouse (C57BL/6J-Lepob). The objective of the present study was to test the hypothesis that a constellation of respiratory complications are attenuated with leptin (i.e., protein product of the ob gene)...
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