Leptin attenuates respiratory complications associated with the obese phenotype.

doi:10.1152/jappl.1998.85.6.2261

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Article

Leptin attenuates respiratory complications associated with the obese phenotype.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Dec 1998

Tankersley C G, O'Donnell C, Daood M J, Watchko J F, Mitzner W, Schwartz A, Smith P

Abstract excerpt

A profile of respiratory complications has been associated with the onset and development of obesity in humans. Similar phenotypes have been routinely demonstrated in genetic animal models of obesity such as the ob mouse (C57BL/6J-Lepob). The objective of the present study was to test the hypothe...

Topics

Animals
Diaphragm
Female
Humans
Leptin
Lung Compliance
Male
Mice
Mice, Inbred C57BL
Mice, Obese
Models, Biological
Myosin Heavy Chains
Obesity
Phenotype
Proteins
Respiratory Mechanics
Respiratory Muscles
Respiratory System

Source

Open in PubMed

Identifiers

PMID: 9843551
DOI: 10.1152/jappl.1998.85.6.2261

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9843551-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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