Article
Modified control of breathing in genetically obese (ob/ob) mice.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Aug 1996
Tankersley C, Kleeberger S, Russ B, Schwartz A, Smith P
Abstract excerpt
Attenuated hypercapnic chemosensitivity and hypoventilation are characteristics periodically associated with human obesity. We tested the hypothesis that ventilatory control is altered by genetic determinants and age-dependent factors that influence the obese phenotype. To this end, the magnitude...
Topics
- Aging
- Animals
- Body Composition
- Cross-Sectional Studies
- Hypercapnia
- Hypoxia
- Longitudinal Studies
- Mice
- Mice, Inbred C57BL
- Mice, Obese
- Obesity
- Phenotype
- Plethysmography, Whole Body
- Respiratory Mechanics
- Weight Gain