Article
Aerobic exercise inhibits obesity-induced respiratory phenotype.
Cytokine - 1 Apr 2018
Aquino-Junior Jefferson Comin Jonco, MacKenzie BreAnne, Almeida-Oliveira Ana Roberta, Martins Ana Carolina, Oliveira-Junior Manoel Carneiro, Britto Auriléa Aparecida, Arantes-Costa Fernanda Magalhaes, Damaceno-Rodrigues Nilsa Regina, Caldini Elia Garcia, de Oliveira Ana Paula Ligeiro, Guadagnini Dioze, Leiria Luiz Osorio, Ricardo Djalma Rabelo, Abdalla Saad Mario Jose, Vieira Rodolfo Paula
Abstract excerpt
PURPOSE: Obesity results in decreased lung function and increased inflammation. Moderate aerobic exercise (AE) reduced lung inflammation and remodeling in a variety of respiratory disease models. Therefore, this study investigated whether AE can attenuate a diet-induced obesity respiratory phenotype; including airway hyper-responsiveness (AHR), remodeling and inflammation. METHODS: Sixty C57Bl/6 male mice were...
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