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Article

c-Met: structure, functions and potential for therapeutic inhibition.

Cancer metastasis reviews - 1 Dec 2003

Ma Patrick C, Maulik Gautam, Christensen James, Salgia Ravi

Abstract excerpt

Studies on signal transduction pathways have generated various promising molecular targets for therapeutic inhibition in cancer therapy. Receptor tyrosine kinases represent an important class of such therapeutic targets. c-Met is a receptor tyrosine kinase that has been shown to be overexpressed and/or mutated in a variety of malignancies. A number of c-Met activating mutations, many of which are located in the...

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Identifiers

PMID: 12884908
DOI: 10.1023/a:1023768811842

Genes

HGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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