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Article

Differential effects of GATA-1 on proliferation and differentiation of erythroid lineage cells.

Blood - 15 Jan 2006

Zheng Jie, Kitajima Kenji, Sakai Eiko, Kimura Tohru, Minegishi Naoko, Yamamoto Masayuki, Nakano Toru

Abstract excerpt

The zinc finger transcription factor GATA-1 is essential for both primitive (embryonic) and definitive (adult) erythropoiesis. To define the roles of GATA-1 in the production and differentiation of primitive and definitive erythrocytes, we established GATA-1-null embryonic stem cell lines in which GATA-1 was able to be conditionally expressed by using the tetracycline conditional gene expression system. The cells...

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Identifiers

PMID: 16174764
DOI: 10.1182/blood-2005-04-1385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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