Article
Transcription factor GATA-1 and erythroid development.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) - 1 Feb 1993
Simon M C
Abstract excerpt
In summary, we derived an experimental system that allows us to dissect the function of GATA-1 in red cell development at a genetic level. We have established the essential nature of GATA-1 during both primitive and definitive erythropoiesis. By ablating the expression of the endogenous GATA-1 ge...
Topics
- Amino Acid Sequence
- Animals
- DNA-Binding Proteins
- Erythrocytes
- Erythroid-Specific DNA-Binding Factors
- Erythropoiesis
- GATA1 Transcription Factor
- Hematopoiesis
- Hematopoietic Stem Cells
- Humans
- Molecular Sequence Data
