Article
Multipotential progenitors of the mammalian enteric nervous system capable of colonising aganglionic bowel in organ culture.
Development (Cambridge, England) - 1 Jan 1999
Natarajan D, Grigoriou M, Marcos-Gutierrez C V, Atkins C, Pachnis V
Abstract excerpt
The enteric nervous system of vertebrates is derived from neural crest cells that invade the gut wall and generate a highly organised network of enteric ganglia. Among the genes that play an important role in ENS development is c-Ret, mutations of which result in failure of formation of enteric g...
Topics
- Animals
- Cell Differentiation
- Digestive System
- Drosophila Proteins
- Enteric Nervous System
- Esophagus
- Mice
- Mutation
- Neuroglia
- Neurons
- Organ Culture Techniques
- Proto-Oncogene Proteins