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Article

Multipotential progenitors of the mammalian enteric nervous system capable of colonising aganglionic bowel in organ culture.

Development (Cambridge, England) - 1 Jan 1999

Natarajan D, Grigoriou M, Marcos-Gutierrez C V, Atkins C, Pachnis V

Abstract excerpt

The enteric nervous system of vertebrates is derived from neural crest cells that invade the gut wall and generate a highly organised network of enteric ganglia. Among the genes that play an important role in ENS development is c-Ret, mutations of which result in failure of formation of enteric ganglia (intestinal aganglionosis). To further understand the development of the mammalian ENS in general and the...

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PMID: 9834195
DOI: 10.1242/dev.126.1.157

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RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Multipotential progenitors of the mammalian enteric nervous system capable of colonising aganglionic bowel in organ culture.PMID 9834195Read ↗

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<i>In Toto</i> imaging of early Enteric Nervous System Development reveals that gut colonization is tied to proliferation downstream of RetSemantic proximity Read ↗

Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epitheliaSemantic proximity Read ↗

Neuron and glia generating progenitors of the mammalian enteric nervous system isolated from foetal and postnatal gut culturesSemantic proximity Read ↗

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Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system.Semantic proximity Read ↗

Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes.Semantic proximity Read ↗

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