Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations of the p53 tumor-suppressor gene and K-ras oncogene in perihilar cholangiocarcinomas from a high-incidence area.

International journal of cancer - 9 Dec 1998

Sturm P D, Baas I O, Clement M J, Nakeeb A, Johan G, Offerhaus A, Hruban R H, Pitt H A

Abstract excerpt

We observed a clustering of cholangiocarcinoma in a part of West Virginia. We analyzed the frequency and type of alterations in the p53 tumor-suppressor gene and the K-ras oncogene to determine whether cholangiocarcinomas from this high-incidence area differ from other cholangiocarcinomas at the molecular level. We studied 12 carcinomas of patients from the high-incidence area (West Virginia group), and 15...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Genes, p53
Share to Genes, ras

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Mutation

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 9833761
DOI: 10.1002/(sici)1097-0215(19981209)78:6<695::aid-ijc5>3.0.co;2-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations of the p53 tumor-suppressor gene and K-ras oncogene in perihilar cholangiocarcinomas from a high-incidence area.PMID 9833761Read ↗

Mutations of the p53 tumor suppressor gene and the ras gene family in intrahepatic cholangiocellular carcinomas in Japan and ThailandSemantic proximity Read ↗

Differences in K-ras and p53 gene mutations among pancreatic adenocarcinomas associated with regional environmental pollution.Semantic proximity Read ↗

Co-mutation of p53, K-ras genes and accumulation of p53 protein and its correlation to clinicopathological features in rectal cancer.Semantic proximity Read ↗

The Role of K-Ras and P53 in Biliary Tract Carcinoma.Semantic proximity Read ↗

High incidence of ras gene mutation in intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

A mutational hot spot in the p53 gene is associated with hepatoblastomas.Semantic proximity Read ↗

Mutational analysis of the p53 and K-ras genes and allelotype study of the Rb-1 gene for investigating the pathogenesis of combined hapatocellular-cholangiocellular carcinomas.Semantic proximity Read ↗

Alteration of the p53 tumor suppressor gene and activation of c-K-ras-2 protooncogene in endometrial adenocarcinoma from Colorado.Semantic proximity Read ↗

p53 and K-RAS alterations in pancreatic epithelial cell lesions.Semantic proximity Read ↗

Analysis of p53 mutations for a mutational signature in human intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

Analysis of genetic changes in intrahepatic cholangiocarcinoma induced by thorotrast.Semantic proximity Read ↗

Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.