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Forskolin up-regulates aromatase (CYP19) activity and gene transcripts in the human adrenocortical carcinoma cell line H295R

1 Jan 2004

Abstract excerpt

A number of conditions related to sex-reversal in boys and men and precocious puberty in girls are caused by estrogen-secreting adrenal tumors. In these tumors, cytochrome P450 aromatase (aromatase) that is encoded in the CYP19 gene is expressed at high levels. To investigate the molecular mechanism of aromatase expression in these adrenal tumors, we characterized the activity, gene transcript and genomic...

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PMID: 14709151
DOI: 10.1677/joe.0.1800125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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