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The Charles River "hairless" rat mutation is distinct from the hairless mouse alleles.

Comparative medicine - 1 Feb 2001

Panteleyev A A, Christiano A M

Abstract excerpt

The Charles River (CR) "hairless" rat is one of the autosomal recessive hypotrichotic animal models actively studied in pharmacologic and dermatologic research. Despite its widespread use, the molecular basis of this monogenic mutation remains unknown, and the skin histologic features of this phenotype have never been described. However, the designation "hairless" has been used as an extension of the hairless...

Topics

Alleles
Animals
Genes, Recessive
Heterozygote
Homozygote
Mice
Mice, Hairless
Models, Animal
Mutation
Phenotype
Rats
Rats, Mutant Strains

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PMID: 11926302

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The Charles River "hairless" rat mutation is distinct from the hairless mouse alleles.PMID 11926302Read ↗

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