Article
Molecular basis for the rhino Yurlovo (hr(rhY)) phenotype: severe skin abnormalities and female reproductive defects associated with an insertion in the hairless gene.
Experimental dermatology - 1 Oct 1998
Panteleyev A A, Ahmad W, Malashenko A M, Ignatieva E L, Paus R, Sundberg J P, Christiano A M
Abstract excerpt
In 1989, mice bearing mutations at the hr (hairless) locus were first proposed as a model for the human hair growth disorder papular atrichia, since in both these mice and in corresponding patients, a complete hair loss develops due to disintegration of the normal follicle structure into dermal c...
Topics
- Animals
- Cysts
- DNA Transposable Elements
- Female
- Genitalia, Female
- Mice
- Mice, Hairless
- Phenotype
- Proteins
- Skin
- Skin Abnormalities
- Skin Diseases
- Transcription Factors