Article
Molecular basis for the rhino (hrrh-8J) phenotype: a nonsense mutation in the mouse hairless gene.
Genomics - 1 Nov 1998
Ahmad W, Panteleyev A A, Sundberg J P, Christiano A M
Abstract excerpt
The hairless (hr) and rhino (hrrh) mutations are autosomal recessive allelic mutations that map to mouse Chromosome 14. Both hairless and rhino mice have a number of skin and nail abnormalities and develop a striking form of total alopecia at approximately 3-4 weeks of age. The molecular basis of...
Topics
- Alleles
- Animals
- Base Sequence
- DNA Mutational Analysis
- DNA Primers
- Genes, Recessive
- Hair Follicle
- Mice
- Mice, Hairless
- Mutation
- Phenotype
- Polymerase Chain Reaction
- Proteins
- Transcription Factors