Article
Penicillin production by glucose-derepressed mutants of Penicillium chrysogenum.
Journal of industrial microbiology - 1 Nov 1990
Chang L T, McGrory E L, Elander R P
Abstract excerpt
Wild-type strains of Penicillium chrysogenum produce lower penicillin V titers in media containing excess glucose. Two mutant strains were isolated and shown to produce normal penicillin V titers in the presence of excess glucose. These strains, designated as glucose-repression insensitive (GRI) mutants, produced higher penicillin V titers than the wild-type strain in media containing lactose as the main...
Topics
- Culture Media
- Fermentation
- Glucose
- Mutation
- Penicillin V
- Penicillium chrysogenum