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Article

Mutations of the DRY motif that preserve beta 2-adrenoceptor coupling.

Receptors & channels - 1 Jan 1998

Seibold A, Dagarag M, Birnbaumer M

Abstract excerpt

The largest family of G protein coupled receptors is characterized by the presence of the DRY motif at the boundary between the third transmembrane region and the second intracellular loop. Inspection of a recent alignment containing 620 receptors reveals that arginine is the best conserved amino acid of this trio. Disease causing receptor mutations have been identified in which this arginine had been replaced by...

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PMID: 9826914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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