Article
Synthesis of glutamine, glycine and 10-formyl tetrahydrofolate is coregulated with purine biosynthesis in Saccharomyces cerevisiae.
Molecular & general genetics : MGG - 1 Aug 1998
Denis V, Daignan-Fornier B
Abstract excerpt
Glutamine, glycine and 10-formyl tetrahydrofolate are consumed during de novo purine biosynthesis. We have found that, in Saccharomyces cerevisiae, synthesis of these cosubstrates is coregulated with synthesis of enzymes of the purine biosynthetic pathway. Analysis of three genes required for syn...
Topics
- Base Sequence
- Binding Sites
- DNA Primers
- DNA, Fungal
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Glutamate-Ammonia Ligase
- Glutamine
- Glycine
- Homeodomain Proteins
- Leucovorin
- Mutation
- Polymerase Chain Reaction
- Promoter Regions, Genetic
- Purines
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins