Article
The Drosophila semushi mutation blocks nuclear import of bicoid during embryogenesis.
Current biology : CB - 19 Nov 1998
Epps J L, Tanda S
Abstract excerpt
The maternal transcript of the anterior segmentation gene bicoid (bcd) is localized at the anterior pole of the Drosophila egg and translated to form a gradient in the nuclei of the syncytial blastoderm embryo after fertilization [1-3]. The nuclear gradient of Bcd protein - a transcription factor - leads to differential expression of zygotic segmentation genes. The rapid nuclear division during this stage [4]...
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