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Article

The Bin3 RNA methyltransferase is required for repression of caudal translation in the Drosophila embryo.

Developmental biology - 1 Apr 2011

Singh Navjot, Morlock Heather, Hanes Steven D

Abstract excerpt

Bin3 was first identified as a Bicoid-interacting protein in a yeast two-hybrid screen. In human cells, a Bin3 ortholog (BCDIN3) methylates the 5' end of 7SK RNA, but its role in vivo is unknown. Here, we show that in Drosophila, Bin3 is important for dorso-ventral patterning in oogenesis and for anterior-posterior pattern formation during embryogenesis. Embryos that lack Bin3 fail to repress the translation of...

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Identifiers

PMID: 21262214
DOI: 10.1016/j.ydbio.2011.01.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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