Article
Activation of nuclear factor kappa B (NF-kappaB) assayed by laser scanning cytometry (LSC).
Cytometry - 1 Nov 1998
Deptala A, Bedner E, Gorczyca W, Darzynkiewicz Z
Abstract excerpt
Nuclear factor kappa B (NF-kappaB)/rel is the family of ubiquitous transcriptional activators involved in regulation of diverse immune and inflammatory responses. It also plays a role in control of cell growth and apoptosis. In its inactive form NF-kappaB remains in the cytoplasm sequestered through interaction with IkappaB protein. Rapid translocation of NF-kappaB from cytoplasm to nucleus that occurs in...
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