Article
Coordinate and independent regulation of alpha B-crystallin and hsp27 expression in response to physiological stress.
Journal of cellular physiology - 1 Apr 1994
Head M W, Corbin E, Goldman J E
Abstract excerpt
alpha-Crystallins share structural and functional properties with the stress protein hsp27. These polypeptides are expressed at low constitutive levels in many tissues including brain, and alpha B-crystallin and hsp27 can accumulate in central nervous system glia in a variety of neurological cond...
Topics
- Animals
- Astrocytes
- Blotting, Northern
- Blotting, Western
- Cadmium
- Cadmium Chloride
- Cell Count
- Cells, Cultured
- Chlorides
- Crystallins
- Fibroblasts
- Gene Expression Regulation
- Genetic Variation
- Heat-Shock Proteins
- Hot Temperature
- Hypoglycemia
- In Situ Hybridization
- RNA, Messenger