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Article

Intermediate filament interactions can be altered by HSP27 and αB-crystallin

1 Jul 1999

Abstract excerpt

HSP27 and alphaB-crystallin are both members of the small heat shock protein family. alphaB-crystalllin has been proposed to modulate intermediate filaments and recently a mutation in alphaB-crystallin has been identified as the genetic basis of desmin related myopathy. This disease is characterised in its pathology by aggregates of intermediate filaments associated with alphaB-crystallin. Here we report that...

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PMID: 10362540
DOI: 10.1242/jcs.112.13.2099

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