Analysis of the incubation periods, induction of obesity and histopathological changes in senescence-prone and senescence-resistant mice infected with various scrapie strains.

doi:10.1099/0022-1317-79-11-2863

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Article

Analysis of the incubation periods, induction of obesity and histopathological changes in senescence-prone and senescence-resistant mice infected with various scrapie strains.

The Journal of general virology - 1 Nov 1998

Carp R I, Meeker H, Sersen E, Kozlowski P

Abstract excerpt

The similarity in histopathological changes seen in scrapie-infected mice and in an uninfected senescence-accelerated mouse strain led to a study in which the mouse strain that is prone to senescence (SAMP8), a strain that is resistant to senescence (SAMR1) and a progenitor strain (AKR) of these...

Topics

Aging
Animals
Genetic Predisposition to Disease
Mice
Mice, Inbred Strains
Obesity
Prions
Scrapie
Virus Replication

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