Article
Interaction between the Msh2 and Msh6 nucleotide-binding sites in the Saccharomyces cerevisiae Msh2-Msh6 complex.
The Journal of biological chemistry - 19 Mar 2010
Hargreaves Victoria V, Shell Scarlet S, Mazur Dan J, Hess Martin T, Kolodner Richard D
Abstract excerpt
Indirect evidence has suggested that the Msh2-Msh6 mispair-binding complex undergoes conformational changes upon binding of ATP and mispairs, resulting in the formation of Msh2-Msh6 sliding clamps and licensing the formation of Msh2-Msh6-Mlh1-Pms1 ternary complexes. Here, we have studied eight mu...
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