Article

The translation attenuating arginine-rich sequence in the extended signal peptide of the protein-tyrosine phosphatase PTPRJ/DEP1 is conserved in mammals

2020-09-07

Abstract excerpt

The signal peptides, present at the N-terminus of many proteins, guide the proteins into cell membranes. In some proteins, the signal peptide contains an extended N-terminal region and a recessed hydrophobic signal sequence. Previously, it was demonstrated that the N-terminally extended signal peptide of the human PTPRJ contains a cluster of arginine residues, which attenuates translation. The analysis of the ort...

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Literature Corpus work: d3a4970d-4e9e-5234-b3c3-4d9055cdc1cc
DOI: 10.1101/2020.09.07.285544

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