Article
Identification of the NKG2D haplotypes associated with natural cytotoxic activity of peripheral blood lymphocytes and cancer immunosurveillance.
Cancer research - 1 Jan 2006
Hayashi Tomonori, Imai Kazue, Morishita Yukari, Hayashi Ikue, Kusunoki Yoichiro, Nakachi Kei
Abstract excerpt
We have previously shown that natural cytotoxic activity of peripheral blood lymphocytes was inversely related to cancer development based on a prospective cohort study. The genetic fraction of cytotoxic activity needs to be clarified, identifying individuals immunogenetically susceptible to cancer. A case-control study within the cohort members was designed: 102 cancer cases with peripheral lymphocyte DNA...
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