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Article

Relation between changes in blood pressure and serum ACE activity after a single dose of enalapril and ACE genotype in healthy subjects.

British journal of clinical pharmacology - 1 Feb 1995

Todd G P, Chadwick I G, Higgins K S, Yeo W W, Jackson P R, Ramsay L E

Abstract excerpt

1. The effects of a single oral dose of enalapril 10 mg on serum ACE activity and blood pressure in relation to the ACE genotype were studied in 27 healthy men, n = 9 each of genotype DD, ID and II, in a parallel group study design. 2. Before treatment serum ACE activity differed significantly between the genotypes, with serum ACE activity 56% higher in DD than II subjects, and the genotype explaining 40% of...

Topics

Adult
Blood Pressure
Enalapril
Genotype
Humans
Male
Middle Aged
Peptidyl-Dipeptidase A

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7742150
DOI: 10.1111/j.1365-2125.1995.tb04419.x
PMCID: PMC1364949

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7742150-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Relation between changes in blood pressure and serum ACE activity after a single dose of enalapril and ACE genotype in healthy subjects.PMID 7742150Read ↗

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