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Article

Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau.

The American journal of pathology - 1 Nov 1998

Spillantini M G, Crowther R A, Kamphorst W, Heutink P, van Swieten J C

Abstract excerpt

Different mutations in the microtubule-associated tau protein gene have recently been identified in several families with hereditary frontotemporal dementia and Parkinsonism (FTDP-17) linked to chromosome 17q21-22. Some families show neuronal and glial deposits containing hyperphosphorylated tau in several brain regions. We have investigated the presence of tau deposits by using a panel of anti-tau antibodies in...

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Identifiers

PMID: 9811325
DOI: 10.1016/S0002-9440(10)65721-5
PMCID: PMC1853390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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