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Article

Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684.

Journal of neuropathology and experimental neurology - 1 Aug 1999

Hulette C M, Pericak-Vance M A, Roses A D, Schmechel D E, Yamaoka L H, Gaskell P C, Welsh-Bohmer K A, Crowther R A, Spillantini M G

Abstract excerpt

Frontotemporal dementia with parkinsonism (FTDP-17) is an autosomal dominant disorder that presents clinically with dementia, extrapyramidal signs, and behavioral disturbances in mid-life and progresses to death within 5 to 10 years. Pathologically, the disorder is characterized by variable neuronal loss and gliosis in the frontal and temporal lobes, limbic structures, and the midbrain. Autopsied individuals from...

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Identifiers

PMID: 10446810
DOI: 10.1097/00005072-199908000-00008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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