Article
[Tau story: from frontotemporal dementia to other tauopathies].
Journal de la Societe de biologie - 1 Jan 2002
Buée Luc, Hamdane Malika, Delobel Patrice, Sambo Anne-Véronique, Bégard Séverine, Ghestem Antoine, Sergeant Nicolas, Delacourte André
Abstract excerpt
Tau proteins belong to the family of microtubule-associated proteins. They are mainly expressed in neurons where they play an important role in the assembly of tubulin monomers into microtubules to constitute the neuronal microtubules network. Tau proteins are translated from a single gene located on chromosome 17. Their expression is developmentally regulated by an alternative splicing mechanism and six...
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