Article
Antigen-induced eosinophilic lung inflammation develops in mice deficient in chemokine eotaxin.
Blood - 15 Nov 1998
Yang Y, Loy J, Ryseck R P, Carrasco D, Bravo R
Abstract excerpt
The mechanisms that regulate the selective infiltration of eosinophils in certain allergic diseases are still poorly understood. The CC chemokine eotaxin is a potent chemoattractant, highly specific for eosinophils. Recent studies have implicated that eotaxin plays an important role in the recrui...
Topics
- Animals
- Antigens
- Bacterial Proteins
- Chemokine CCL11
- Chemokines, CC
- Chemotaxis, Leukocyte
- Cytokines
- Dextrans
- Escherichia coli
- Gene Targeting
- Genes, Reporter
- Mice
- Mice, Knockout
- Mice, Transgenic
- Microspheres
- Organ Specificity
- Ovalbumin
- Phenotype