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Article

Regulation of Eosinophil Recruitment and Allergic Airway Inflammation by Tropomyosin Receptor Kinase A.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2020

Dileepan Mythili, Ge Xiao Na, Bastan Idil, Greenberg Yana G, Liang Yuying, Sriramarao P, Rao Savita P

Abstract excerpt

Eosinophilia is a hallmark of allergic airway inflammation (AAI). Identifying key molecules and specific signaling pathways that regulate eosinophilic inflammation is critical for development of novel therapeutics. Tropomycin receptor kinase A (TrkA) is the high-affinity receptor for nerve growth factor. AAI is associated with increased expression of TrkA by eosinophils; however, the functional role of TrkA in...

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Identifiers

PMID: 31871023
DOI: 10.4049/jimmunol.1900786
PMCID: PMC7058110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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