Article
Eosinophil activities modulate the immune/inflammatory character of allergic respiratory responses in mice.
Allergy - 1 Mar 2014
Jacobsen E A, Lesuer W E, Willetts L, Zellner K R, Mazzolini K, Antonios N, Beck B, Protheroe C, Ochkur S I, Colbert D, Lacy P, Moqbel R, Appleton J, Lee N A, Lee J J
Abstract excerpt
BACKGROUND: The importance and specific role(s) of eosinophils in modulating the immune/inflammatory phenotype of allergic pulmonary disease remain to be defined. Established animal models assessing the role(s) of eosinophils as contributors and/or causative agents of disease have relied on congenitally deficient mice where the developmental consequences of eosinophil depletion are unknown. METHODS: We developed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.