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Article

Eosinophil adoptive transfer system to directly evaluate pulmonary eosinophil trafficking in vivo.

Proceedings of the National Academy of Sciences of the United States of America - 9 Apr 2013

Wen Ting, Besse John A, Mingler Melissa K, Fulkerson Patricia C, Rothenberg Marc E

Abstract excerpt

Most in vivo studies of granulocytes draw conclusions about their trafficking based on examination of their steady-state tissue/blood levels, which result from a combination of tissue homing, survival, and egress, rather than direct examination of cellular trafficking. Herein, we developed a unique cell transfer system involving the adoptive transfer of a genetically labeled, bone-marrow-derived unique...

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PMID: 23536294
DOI: 10.1073/pnas.1220572110
PMCID: PMC3625276

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CCR3

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