Article
Association between polymorphisms at N-acetyltransferase 1 (NAT1) & risk of oral leukoplakia & cancer.
The Indian journal of medical research - 1 Oct 2012
Majumder Mousumi, Ghosh Saurabh, Roy Bidyut
Abstract excerpt
BACKGROUND & OBJECTIVES: N-acetyltransferases 1 and 2 (NAT1 and NAT2) are important enzymes for metabolism of tobacco carcinogens. Due to polymorphisms, improper activities of these enzymes might lead to the formation of DNA adducts that may modulate risk of tobacco related oral precancer and cancer. Previously, it was shown that NAT2 polymorphisms did not modulate the risk of oral precancer and cancer. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
