Article
Persistent expansion, in a human immunodeficiency virus-infected person, of V beta-restricted CD4+CD8+ T lymphocytes that express cytotoxicity-associated molecules and are committed to produce interferon-gamma and tumor necrosis factor-alpha.
The Journal of infectious diseases - 1 Oct 1998
Weiss L, Roux A, Garcia S, Demouchy C, Haeffner-Cavaillon N, Kazatchkine M D, Gougeon M L
Abstract excerpt
The present study describes the persistent expansion of a subpopulation of circulating double-positive CD4+CD8+ T cells in a human immunodeficiency virus (HIV)-infected person over 8 years. The percentage of double-positive cells was remarkably stable with time and was not related to HIV plasma v...
Topics
- CD4 Antigens
- CD8 Antigens
- HIV Infections
- Homosexuality
- Humans
- Interferon-gamma
- Lymphocyte Activation
- Male
- Middle Aged
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta