Article
Development of a questionnaire method to discriminate between typical and atypical genotypes of low Km aldehyde dehydrogenase in a Japanese population.
Alcoholism, clinical and experimental research - 1 Oct 1998
Takeshita T, Morimoto K
Abstract excerpt
Nearly half of all Orientals exhibit aversive symptoms, such as "Oriental flushing" or palpitation, during alcohol consumption. This high alcohol sensitivity among Orientals has been attributed to a highly prevalent polymorphism in low Km aldehyde dehydrogenase (ALDH2). In the present study, we a...
Topics
- Adult
- Alcohol Drinking
- Aldehyde Dehydrogenase
- Aldehyde Dehydrogenase, Mitochondrial
- Ethnicity
- Female
- Flushing
- Genetics, Population
- Genotype
- Humans
- Male
- Middle Aged
- Polymorphism, Genetic
- Regression Analysis
- Surveys and Questionnaires