Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population.

doi:10.1007/BF00208273

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Article

Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population.

Human genetics - 1 Sept 1994

Takeshita T, Morimoto K, Mao X, Hashimoto T, Furuyama J

Abstract excerpt

A deficiency in low Km aldehyde dehydrogenase (ALDH2) is regarded as the main factor responsible for "Oriental flushing" and other symptoms due to alcohol sensitivity. In this study, the relationship of the ALDH2 genotype to alcohol-associated symptoms and drinking behavior was investigated in 52...

Topics

Adult
Alcohol Drinking
Aldehyde Dehydrogenase
Base Sequence
DNA Primers
Ethanol
Female
Genotype
Humans
Hypersensitivity
Japan
Leukocytes
Male
Molecular Sequence Data
Polymerase Chain Reaction

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