Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population.

Human genetics - 1 Sept 1994

Takeshita T, Morimoto K, Mao X, Hashimoto T, Furuyama J

Abstract excerpt

A deficiency in low Km aldehyde dehydrogenase (ALDH2) is regarded as the main factor responsible for "Oriental flushing" and other symptoms due to alcohol sensitivity. In this study, the relationship of the ALDH2 genotype to alcohol-associated symptoms and drinking behavior was investigated in 524 Japanese workers, using a new, rapid, and nonisotopic polymerase chain reaction (PCR) method. Differences in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Molecular Sequence Data
Share to Base Sequence
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ethanol

Share to Genotype

Share to Leukocytes

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 8076934
DOI: 10.1007/BF00208273

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population.PMID 8076934Read ↗

Development of a questionnaire method to discriminate between typical and atypical genotypes of low Km aldehyde dehydrogenase in a Japanese population.Semantic proximity Read ↗

The contribution of polymorphism in the alcohol dehydrogenase beta subunit to alcohol sensitivity in a Japanese population.Semantic proximity Read ↗

Polymorphism in ALDH2-genotype in Japanese men and the alcohol-blood pressure relationship.Semantic proximity Read ↗

Analysis of aldehyde dehydrogenase 2 gene polymorphism and ethanol patch test as a screening method for alcohol sensitivity.Semantic proximity Read ↗

Molecular genetics of human aldehyde dehydrogenase.Semantic proximity Read ↗

Alcohol consumption by orientals in North America is predicted largely by a single gene.Semantic proximity Read ↗

Low Km aldehyde dehydrogenase (ALDH2) polymorphism, alcohol-drinking behavior, and chromosome alterations in peripheral lymphocytes.Semantic proximity Read ↗

[Aldehyde dehydrogenase (ALDH2) polymorphism and drinking behavior].Semantic proximity Read ↗

Genotypes of alcohol-metabolizing enzymes in Mexicans with alcoholic liver cirrhosis.Semantic proximity Read ↗

The ALDH2 genotype, alcohol intake, and liver-function biomarkers among Japanese male workers.Semantic proximity Read ↗

Alcohol dehydrogenase: enzymology and metabolism.Semantic proximity Read ↗

Genetic Polymorphisms of the Mitochondrial Aldehyde Dehydrogenase ALDH2 Gene in a Large Ethnic Hakka Population in Southern China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.