Article
Epigenetic factors regulate the NPY expression in rat cortical neurons.
Regulatory peptides - 25 Sept 1998
Wirth M J, Gorba T, Wahle P
Abstract excerpt
The NPY phenotype expressed in a subset of rat neocortical neurons is influenced by a variety of epigenetic factors. In the present study, we analyzed the role of synaptically driven spontaneous bioelectric (action potential) activity (SBA) and neurotrophic factors. Our model systems are organotypic monocultures of visual cortex which either grow as spontaneously active cultures or as activity-blocked cultures to...
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