Article
Phenotype specification of cortical neurons during a period of molecular plasticity.
The European journal of neuroscience - 1 Dec 1997
Obst K, Wahle P
Abstract excerpt
The transient expression of neuropeptide transmitters is a common feature of the developing cortex. We have now analysed the role of cortical afferents in shaping the neurochemical architecture of rat visual cortex using organotypic cultures. Deafferented cortex monocultures prepared from newborn rats reveal a constant NPY mRNA expression in 6-8% of all cortical neurons up to 90 days in vitro (DIV). In contrast,...
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