Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phospholipases: in search of a genetic base of schizophrenia.

Prostaglandins, leukotrienes, and essential fatty acids - 1 Aug 1996

Hudson C J, Lin A, Horrobin D F

Abstract excerpt

Evidence from a variety of clinical and biochemical sources indicates alterations in phospholipid synthesis and activity in schizophrenia. We review a recent study which suggests that a genetic variant near the promotor region of the gene for cytosolic phospholipase A2, the rate-limiting enzyme in the synthesis of prostaglandins from arachidonic acid (AA), is associated with schizophrenia. These findings are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cohort Studies
Share to Cytosol

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to Membrane Lipids

Share to Reference Values

Share to Schizophrenia

Source

Identifiers

PMID: 8888134
DOI: 10.1016/s0952-3278(96)90156-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phospholipases: in search of a genetic base of schizophrenia.PMID 8888134Read ↗

Red cell membrane fatty acids, cytosolic phospholipase-A2 and schizophrenia.Semantic proximity Read ↗

Lack of association between schizophrenia and a polymorphism close to the cytosolic phospholipase A2 gene.Semantic proximity Read ↗

Association of the Ban I dimorphic site at the human cytosolic phospholipase A2 gene with schizophrenia.Semantic proximity Read ↗

Association studies of cytosolic phospholipase A2 polymorphisms and schizophrenia among two independent family-based samples.Semantic proximity Read ↗

Association between BanI genotype and increased phospholipase A2 activity in schizophrenia.Semantic proximity Read ↗

Allelic association analysis of phospholipase A2 genes with schizophrenia.Semantic proximity Read ↗

BanI polymorphism of the cytosolic phospholipase A2 gene may confer susceptibility to the development of schizophrenia.Semantic proximity Read ↗

Systematic screening of the LDL-PLA2 gene for polymorphic variants and case-control analysis in schizophrenia.Semantic proximity Read ↗

[Study on the genetic association between the polymorphism of cytosolic phospholipase A2 family genes and schizophrenia].Semantic proximity Read ↗

Lack of association between schizophrenia and the phospholipase-A(2) genes cPLA2 and sPLA2.Semantic proximity Read ↗

BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder.Semantic proximity Read ↗

Niacin skin flush test: a research tool for studying schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.