Article
K-ras gene mutations in the diagnosis of fine-needle aspirates of pancreatic masses: prospective study using two techniques with different detection limits.
Clinical chemistry - 1 Nov 1998
Mora J, Puig P, Boadas J, Urgell E, Montserrat E, Lerma E, González-Sastre F, Lluís F, Farré A, Capellá G
Abstract excerpt
Detection of K-ras mutations may be useful in the evaluation of pancreatic cancer. The aim of this study was to assess, in a prospective design, the diagnostic utility of K-ras mutation analysis in 62 consecutive fine-needle aspirates of pancreatic masses, using two PCR-based techniques-standard...
Topics
- Aged
- Biopsy, Needle
- Codon
- Female
- Genes, ras
- Humans
- Male
- Middle Aged
- Mutation
- Pancreas
- Pancreatic Neoplasms
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single-Stranded Conformational