Article
Quantitative analysis of K-ras gene mutation in pancreatic tissue obtained by endoscopic ultrasonography-guided fine needle aspiration: clinical utility for diagnosis of pancreatic tumor.
The American journal of gastroenterology - 1 Sept 2002
Tada Minoru, Komatsu Yutaka, Kawabe Takao, Sasahira Naoki, Isayama Hiroyuki, Toda Nobuo, Shiratori Yasushi, Omata Masao
Abstract excerpt
OBJECTIVES: Endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA) has become established in the diagnosis of pancreatic cancer. The combination of pathological diagnosis and analysis for mutant K-ras gene was investigated to improve the accuracy of diagnosis. METHODS: EUS-FNA was performed in 34 patients with pancreatic masses (26 adenocarcinomas and eight chronic pancreatitis). Mutant ras gene was...
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