Article
Interaction of abl and raf with IL-7 signaling pathway and transformation of pre-B cells from resistant mice.
Oncogene - 22 Oct 1998
Hilbert D M, Theisen P W, Rudikoff E K, Bauer S R
Abstract excerpt
After in vivo inoculation with abl/myc- and raf/myc-containing retroviruses, BALB/c mice predominantly develop late stage B cell tumors (plasmacytomas) and less frequently develop earlier B-lineage tumors while DBA/2 mice do not develop B-lineage tumors. We have investigated the in vitro tumorigenic potential of these viruses using cultured normal pre-B cell lymphocytes from both BALB/c and DBA/2 mice....
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