Article
Interaction of abl and raf with IL-7 signaling pathway and transformation of pre-B cells from resistant mice.
Oncogene - 22 Oct 1998
Hilbert D M, Theisen P W, Rudikoff E K, Bauer S R
Abstract excerpt
After in vivo inoculation with abl/myc- and raf/myc-containing retroviruses, BALB/c mice predominantly develop late stage B cell tumors (plasmacytomas) and less frequently develop earlier B-lineage tumors while DBA/2 mice do not develop B-lineage tumors. We have investigated the in vitro tumorige...
Topics
- Animals
- B-Lymphocytes
- Cell Transformation, Neoplastic
- Cell Transformation, Viral
- Cells, Cultured
- Gene Expression
- Genetic Vectors
- Immunity, Innate
- Interleukin-7
- Lymphoma, B-Cell
- Mice
- Mice, Inbred BALB C
- Mice, Inbred DBA
- Mice, SCID
- Phenotype
- Proto-Oncogene Proteins c-abl
- Proto-Oncogene Proteins c-myc
- Proto-Oncogene Proteins c-raf
