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Article

Association of Human FcγRIIa (CD32) Polymorphism with Susceptibility to and Severity of Meningococcal Disease

1 Oct 1998

Abstract excerpt

Phagocytosis of bacteria constitutes an important defense mechanism against invasive bacterial diseases. Efficacy of phagocytosis by polymorphonuclear neutrophils is known to vary between allotypes of Fc gamma RIIa (a class of Fc receptors for immunoglobulins that is constitutively expressed on neutrophils). We compared the distribution of Fc gamma RIIa-R131 and Fc gamma RIIa-H131 allotypes in 98 Slavic...

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PMID: 9798027
DOI: 10.1086/514935

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