The Fcγ receptor IIA-H/H131 genotype is associated with bacteremia in pneumococcal community-acquired pneumonia.

doi:10.1097/CCM.0b013e31820eda74

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Article

The Fcγ receptor IIA-H/H131 genotype is associated with bacteremia in pneumococcal community-acquired pneumonia.

Critical care medicine - 1 Jun 2011

Solé-Violán Jordi, García-Laorden M Isabel, Marcos-Ramos José Alberto, de Castro Felipe Rodríguez, Rajas Olga, Borderías Luis, Briones M Luisa, Herrera-Ramos Estefanía, Blanquer José, Aspa Javier, Florido Yanira, García-Bello Miguel Angel, Ferrer-Agüero José María, Sologuren Ithaisa, Rodriguez-Gallego Carlos

Abstract excerpt

OBJECTIVE: To assess the potential association of the functional polymorphism rs1801274 in the receptor IIa for the Fc portion of immunoglobin G (FcγRIIa) gene (FCGR2A-H131R) with the susceptibility to and the severity of community-acquired pneumonia (CAP). DESIGN: Multicenter prospective and observational study. SETTING: Four university hospitals in Spain. PATIENTS: FCGR2A-H131R polymorphism was determined in...

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PMID: 21317643
DOI: 10.1097/CCM.0b013e31820eda74

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